According to Father Juan Paguere, it was just a wide and long stretch of virgin land located at the southernmost end of the province of Cagayan.

It was named "Cabugag" or in short Cabug, the dialect term for hunchback for the first settler was a man with this deformity.

The Cagayan River which flowed close to the barrio site gradually changed its course and moved towards Cataggaman as flood plains were formed.

The non-Christian inhabitants called Kalingas gradually deserted the barrio and migrated westward to the Mountain Province.

The population unanimously adopted "Nuestra Señora de las Nieves" as its patron Saint.

Enrile has a land area of 18,451.3 hectares unevenly distributed to the 22 barangays of the municipality and predominantly agricultural where the majority of its inhabitants derive their income from farming.

Area with low elevation is about 20 meters above sea level at the Eastern part which lies close to the river boundaries.

One estimate of the town's production places a volume of 1,800 metric tons per year or 8 to 10 percent of the national supply.

"With improved production and yield, Enrile may be able to fill up a portion, if not all, of the import requirement for peanut of 15,060 metric tons," Alviar added.

Passenger jeepneys, tricycles and other private transportation vehicles service all routes within and outside Enrile.

Don Cornelio Bunagan – 1896 – 1898 The Schools Division of Cagayan governs the town's public education system.