Francini started his musical career when he joined the orchestra of Ehlert, which included Héctor Stamponi and Armando Pontier, and performed on a well-known afternoon programme on Radio Prieto.
Inspired by Aníbal Troilo, the orchestra evolved instrumentally with tangos such as Arrabal, La beba, Lo que vendrá, Pa'que se acuerden de mí, Para lucirse, Pichuco, Tigre viejo and A Zárate.
After this he set up a duo with Hector Stamponi, whilst at the same time establishing his own orchestra with the pianist Juan Jose Paz, the bandoneonist Julio Ahumada and the singer Alberto Podestá .
In 1954 he took part in a homage to Juan Carlos Cobián in a quintet comprising the tango musicians Aníbal Troilo on bandoneon, Roberto Grela on guitar, Kicho Díaz on double bass and Horacio Salgán on piano.
In 1963 he joined the pianist Orlando Trípodi, together with Armando Pontier, Domingo Federico, Alberto Podestá and Raúl Berón in La Orquesta de las Estrellas, directed by Miguel Caló and later in 1970 he formed a sextet, with the bandoneonist Néstor Marconi in charge of arrangements, which appeared at Caño 14 in Buenos Aires, on television and recorded an album.