[3] During that time, the foundation was laid for the establishment of an Eastern Orthodox Eparchy in that region, under the jurisdiction of the Serbian Patriarchate of Peć.

By the end of 15th century much of the region was conquered by Ottoman Turks who organized the territory into a province called the Sanjak of Zvornik.

Between 1526 and 1541, during the attempt of Metropolitan Pavle of Smederevo to restore the Serbian Patriarchate of Peć, Eparchy of Zvornik and its bishop Teofan were also included in local ecclesiastical disputes with Archbishopric of Ohrid.

Since 1878, territory of Bosnia and Herzegovina was under the occupation of Austria-Hungary, but under the Church Convention of 1880 all Eastern Orthodox eparchies remained under supreme ecclesiastical jurisdiction of Ecumenical Patriarchate of Constantinople.

The process of unification was completed in 1920 and since then Eparchy of Zvornik and Tuzla remains part of the united Serbian Orthodox Church.