Colonel Epes Sargent (July 12, 1690 – December 6, 1762) was an American landowner, merchant, politician and military officer from Gloucester, Massachusetts.

[4] His maternal grandparents were Mary Eppes (1629–1692) and Peter Duncan (1629–1716), who emigrated from England to Massachusetts.

[5] He served as a colonel in the Massachusetts militia before the Revolutionary War and was a justice of the general session court for more than thirty years.

[3] Before Esther's death, she gave birth to:[3] After Esther's death, Epes Sargent married Catherine (née Winthrop) Brown (1711–1781), the widow of Samuel Brown and the daughter of Ann Dudley and John Winthrop (1681–1747), on August 10, 1744, and moved to Salem, Massachusetts.

Together, they were the parents of:[3] Sargent died on December 6, 1762, in Salem[6] and his remains were removed to Gloucester for burial.