Ephraim Ruebush (September 26, 1833 – November 18, 1924) was a music teacher, publisher, and co-founder of the Ruebush-Kieffer Company, one of the largest and most influential publishers of gospel song books in the United States.
In September 1853, he traveled to Singers Glen, Virginia, to study music and printing under Joseph Funk.
With his brother-in-law, Aldine Silliman Kieffer, he founded the Kieffer-Ruebush music company in Dayton, Virginia.
This became one of the largest and most influential gospel music companies of its day, printing songbooks into the 1940s.
Ruebush died on November 18, 1924, and is buried in Dayton.