He seems to have been an earlier supporter of astrology, which, though derided by many Greek intellectuals, came to be accepted after Alexander the Great conquered major parts of the Near East.
[3] Pliny the Elder writes that Epigenes attests to the fact that the Chaldeans preserved astral observations in inscriptions upon brick tiles (coctilibus laterculis) extending to a period of 720 years.
Pliny calls Epigenes a writer of first-rate authority (gravis auctor imprimis).
[2] Epigenes refined the study of his chosen field, defining Saturn, for example, as "cold and windy."
Along with Apollonius of Myndus and Artemidorus of Parium,[5] he boasted of having been instructed by the Chaldean priest-astrologers.