He was a professor of the Department of Biblical and Philological Disciplines of the Kyiv Orthodox Theological Academy [uk].

[5] Native of southern Ukraine, Serhii Petrovych Dumenko was born on 3 February 1979 in Vovkove, Berezivka Raion near Odesa.

He graduated as a doctor of theology in 2003 having successfully defended his PhD thesis on the "Formation of church-canonical collections in the Donician period and their characteristics".

From 26 August 2003 to 31 December 2005 he was a teacher of the Rivne Seminary, and also held the post of senior assistant inspector.

Rivne Orthodox) Internet portal, and was also a member of the editorial board of the religious newspaper Dukhovna Nyva (transl.

Since the academic year 2007, he has been a teacher at the Kyiv Orthodox Theological Academy [uk], and was appointed head of the philology department.

[6] On 21 December 2007, with the blessing of Patriarch Filaret, Archbishop Dimitriy of Pereiaslav-Khmelnytskyi Epiphanius received a tonsure as a monk in the Michael's Golden-Domed Monastery.

On 21 October 2009, at the Holy Synod of the UOC-KP he was elected Bishop of Vyshhorod, vicar of the Kyiv diocese.

By the decision of the Holy Synod of the UOC-KP from 27 July 2010, he was appointed rector of the Kyiv Orthodox Theological Academy and the governor of the Pereiaslav-Khmelnytsky diocese.

[10] On August 21, 2020, on St. Michael's Square in Kyiv, Metropolitan Epiphanius consecrated the renovated Wall of Remembrance of Heroes.

[11] He also consecrated the church on August 20 in honor of St. Nectarios of Aegina in the village of Khutir Yasny in Kyiv region.

[24] In the same liturgy, Metropolitan Epiphany also omitted Patriarch Kirill of Moscow from the list of brother primates with whom he is in communion who are usually commemorated at the Great Entrance.

[35] After the tomos was signed, Metropolitan Epiphanius made a speech, in which he declared about Poroshenko: "Your name, Mr President, will forever go down in the history of the Ukrainian people next to the names of the rulers, of our prince Volodymyr the Great, Yaroslav the Wise, Kostyantyn Ostrozky and Hetman Ivan Mazepa".

[39][40][41][42] The tomos, signed by all members of the synod of the Ecumenical Patriarchate, was brought back to Ukraine on the morning of 10 January 2019.

[63][64] A conflict erupted between Filaret and Epiphanius because of disagreements concerning the model of governance, the management of the diaspora, and the name and the statute of the OCU.

"[69][70][71] Following the February 2022 Russian invasion and escalation of the Russo-Ukrainian War, Archbishop Daniel of the Ukrainian Orthodox Church of the USA reported that Epiphanius planned to remain in Ukraine during the fighting.

[73] The Metropolitan repeatedly condemned Russia's actions, asking for help from the international community[74] and suggesting second Nuremberg trials to prosecute the crimes committed against Ukraine.

[6] 2019 Athenagoras Human Rights Award[83][84] In March 2019, he was named an Honorary doctor of the National Pedagogical Dragomanov University.