The origins date back to the missionaries of the Pallottines, who were the first to feel the need to meet to discuss issues related to the evangelization of the country.
The CENC is a member of the Association of Regional Conferences of the Region of Central Africa and Symposium of Episcopal Conferences of Africa and Madagascar (SECAM).
The First World War and the expulsion of the German missionaries from the country, the outlook changed.
In June 1949, held in Yaounde, the first plenary lecture of the Ordinaries of the missions of the French-speaking Cameroon: five bishops took part under the chairmanship of the Apostolic Delegate.
The Second Vatican Council gave great impetus to the formation of the episcopal conferences: the Cameroonian bishops met several times in Rome, on November 24, 1962 and officially founded the Episcopal Conference of Cameroon, who today took the official name in 1972 to its constitution, drawn up already this year, were approved by the Holy See in 1986.