[1] There are three types:[2] X-linked dominant erythropoietic protoporphyria is a relatively mild version of porphyria with the predominant symptom being extreme photosensitivity causing severe itching and burning sensation of the skin due to the buildup of protoporphyrin IX.
Levels of free protoporphyrin decreased significantly as there was iron available for the FECH to produce heme.
[citation needed] X-linked dominant erythropoietic protoporphyria is distinct from EPP in that there is no overload of Fe2+ ions.
XDEPP is characterized by a buildup of protoporphyrin IX caused by in increased level of function in the ALAS2 enzyme.
[citation needed] The diagnosis is confirmed by finding increased red blood cell and plasma protoporphyrin levels.