The Escuela Superior Politécnica del Litoral (ESPOL) is a public university located in Guayaquil, Guayas Province in Ecuador.

The school was created on October 24, 1958, through Executive Decree 1664 by President Camilo Ponce Enriquez,[1] as a higher education institution.

In 1969, the Quinto Guayas Battalion gave ESPOL the area between the Simón Bolívar embankment and Loja Street, where the four engineering departments were located.

In 1973, the Ecuadorian marines moved from their base in Guayaquil, and in their place, new installations for the Facultad de Ingenieria Maritima y Ciencias del Mar were constructed.

[5] In 2022 Cecilia Paredes Verduga was re-elected for a second five-year term as rector by the students, teaching ESPOL staff and employees.

The Campus Via de la Costa, located on the coast of the Santa Elena province, hosts the CENAIM-ESPOL Foundation and maritime-related research and degree programs.

[7] The Polytechnic High School (Colegio Politecnico) is a secondary educational institution linked and colocated with the university.

Undergraduate academics include the School of Design and Visual Communication of ESPOL (previously known as Escuela de Diseño y Comunicaciónis', currently Faculty), which is associated with the broad field of Arts and Humanities of the International Standard Classification of Education (ISCED).