Espe is a manor house and estate located at Boeslunde, between Korsør and Skælskør, Slagelse Municipality, some 100 kilometres southwest of Copenhagen.

In 1561, Espe was ceded to chancellor Johan Friis in exchange for property at Korsør.

The estate was probably later acquired by Anders Hansen, since his widow, Anne Marie Andersdatter, is recorded as the owner in 1689.

[2] Anne Marie Andersdatter sold Espe in 1723 to Mette Rosenkrantz (died 1630).

It was then sold by auction in 1730 for 10,000 rigsdaler to colonel lieutenant Christian Frederik de Boysset.

He sold Espe by auction 1736 for 7,810 rigsdaler to merchant in Sorø Poul Schnabel.

In 1810, after having changed hands three more times, Espe was acquired by Otto Joachim Moltke.

He died just five years later and his widow then managed the estate on behalf of their newborn son, Adam Gottlob Moltke.