Ethmia spyrathodes is a moth in the family Depressariidae first described by Edward Meyrick in 1922.

It is found in São Tomé and Príncipe, off the western coast of Central Africa.

The forewings are ochreous white with black markings: three spots on the basal portion of the costa, the middle one transverse and reaching halfway across the wing, a narrow irregular fascia at one-fourth with the posterior edge acute prominent in the disc and a small round spot beneath the fold before the middle.

There is an irregular oblique blotch from the costa before the middle connected in the disc with a moderate irregular fascia from four-fifths of the costa to near the dorsum at three-fourths, dilated on the costa and touching a round spot towards the termen above the middle.

The hindwings are light grey, thinly scaled anteriorly, darker towards the termen.