Eudokia Makrembolitissa[4] (Greek: Εὐδοκία Μακρεμβολίτισσα, romanized: Evdokía Makremvolítissa) was a Byzantine empress by her successive marriages to Constantine X Doukas and Romanos IV Diogenes.

She acted as regent of her minor son, Michael VII in 1067, and resigned her regency by marriage to Romanos IV Diogenes.

[5] John, who belonged to the aristocracy of Constantinople, allied with Cerularius in 1040 to conspire against Emperor Michael IV, but their plan was stopped soon after.

[3][15][16] According to the contemporary Michael Psellos, Eudokia "succeeded [Constantine X] as supreme ruler, she did not hand over the government to others... she assumed control of the whole administration in person.

One inscription on a silver reliquary calls her "Great Empress of the Romans" (megalē basilis tōn Romaiōn), suggesting that she had a higher status than her sons (who were only basileus).

[21] Eudokia had sworn on Constantine's deathbed not to remarry, and she even made the oath in the presence of patriarch John VIII Xiphilinos.

[3][4] Another of Eudokia and Constantine's sons, Andronikos Doukas, was also made co-emperor by Romanos IV, although he had been excluded from power by his own father, mother, and brothers.

[30] On 26 August 1071, Romanos IV faced Alp Arslan, sultan of the Seljuk Empire, at the decisive Battle of Manzikert.

[31][32] The Byzantine army was destroyed and the emperor himself was captured, partly because of the treachery of general Andronikos, John Doukas's son.

[35] On 1 October the Senate declared Romanos IV deposed and proclaimed Eudokia and Michael VII as joint rulers.

[37] The new regime only lasted one month,[b] when Eudokia's opposition became strong enough to depose her, especially after news of Romanos release arrived at the capital.

[38] Soon after her deposition, she allied with Anna Dalassene, a sister-in-law of Isaac I Komnenos who had also been exiled,[38] to restore Romanos IV and depose John Doukas.

It is prefaced by an address to her husband, Romanos Diogenes, and the work is described as "a collection of genealogies of gods, heroes, and heroines, of their metamorphoses, and of the fables and stories respecting them found in the ancients; containing also notices of various philosophers".