He was a postdoctoral research associate with Wolfgang Pauli at the Austrian–German Science Foundation, Federal Institute of Technology (ETH) Zurich and University of Leipzig, with Werner Heisenberg from 1930 to 1931.

He is noted for several pioneering discoveries that advanced the field of polymer physics, which was recognised by the award of the Bingham Medal for rheology in 1965.

[5] A book, co-edited by his long-time friend and colleague Professor J. E. (Jim) Mark of the University of Cincinnati, was intended to celebrate Eugene Guth's 85th birthday, but subsequently was published as a memorial.

The book is entitled "Elastomeric Polymer Networks", Prentice Hall Publishers, 1992, ISBN 0-13-249483-3.

The oval picture to the right is found in the inside preface to that collected papers volume.