Euphrosyne of Greater Poland (Polish: Eufrozyna wielkopolska; 1247/50 – 17/19 February 1298) was a Greater Poland princess, member of the House of Piast and abbess of St. Clara in Trzebnica.
The religious environment of Bolesław's court certainly impacted in his nieces; all three who remained unmarried (Euphrosyne and her sisters, twins Anna and Euphemia) took the veil.
Euphrosyne became a nun in the Cistercian monastery of Trzebnica, and in 1278 she became the Abbess.
Documentation from the years 1285–1297 shows a high activity of Euphrosyne as Abbess, especially in economic matters of the monastery.
Presumably, during her sovereignty, in Trzebnica was transcribed the Life of her maternal great-grandmother, St. Hedwig of Andechs.