One of her best known film roles is the character Kate from Czech Fairy tale Playing with the Devil (1956) directed by Josef Mach.

He father, Antonín Klepáč, was a dancer at the National Theatre, her mother Kamila Klepáčová (née Vlášková) was a freelance dancer and actress (she danced in the Vest Pocket Revue at the Liberated Theatre of Jiří Voskovec and Jan Werich).

As many other actors from Prague, Eva Klepáčová began her acting career in Disman’s Children Art Radio Ensemble.

Thanks to her nice voice and cultivated speech, Eva Klepáčová worked as an occasional presenter in Czechoslovak Television, practically from the very beginning of its existence.

Together with her husband, Josef Zíma, she successfully dubbed, among many others, the main character of Nastenka, from the Russian Fairy tale Jack Frost (1964).