The first OYM yearly meeting was on August 14, 1813 at Short Creek, with Horton Howard presiding.
In 1971 Ohio Yearly Meeting (Damascus) became Evangelical Friends Church – Eastern Region (EFCER).
By the 1870s, a noted evangelist, David B. Updegraff, supported baptism and communion in Friends churches.
The Evangelical Friends Church - Eastern Region was heavily influenced by the leadership of J. Walter and Emma Malone.
Into the twentieth century, EFCER expanded its churches, missions, leaders and prominence amongst evangelicals worldwide.