F. B. Culley Generating Station is a 369 megawatt (MW) coal power plant located southeast of Newburgh in Warrick County, Indiana.

It sits on the north bank of Ohio River, immediately adjacent and upstream of the Warrick Power Plant, and is owned and operated by Vectren (formerly Southern Indiana Gas and Electric Company).

The unit closed in 2006 in order to comply with the Environmental Protection Agency's (EPA) Clean Air Interstate Rule.

[4] In 1992, Vectren installed a flue-gas desulfurization (FGD) system on Units 2 and 3 to reduce sulfur dioxide (SO2) emissions and satisfy the requirement of the EPA's Acid Rain Program.

[2] From 2001 to 2005, Vectren installed four selective catalytic reduction (SCR) devices on the coal-fired units, which successfully cut nitrogen oxide (NOx) emissions by 80 percent.