Farafenni or Farafegni is a town in the Gambia, lying on the Trans-Gambia Highway in the North Bank Division, just south of the border with Senegal.

Farafenni is the site of a recently built hospital and also contains a military base which was attacked in 1995 by six men later claiming to be Sanyang's collaborators.

Farafenni Upper Basic School is sponsored by John Cabot Academy in Bristol, UK.

The lumo place is located at the outskirts of the town, adjacent to the Farafenni Stadium.

Farafenni is at the northern end of the segment of the Trans-Gambia Highway containing the Senegambia Bridge.