[3] While located in Euless and Bedford, FM 157 is known as Industrial Boulevard, while in Fort Worth, it is known as Collins Street.

In Arlington, the route continues on North Collins, Division, and South Cooper Streets.

The Texas Department of Transportation (TxDOT) designated the route in 1945, and redesignated the portion traveling from SH 121 to US Bus.

FM 157 begins at its southern terminus, a three-way intersection with Farm to Market Road 66, in Maypearl.

After the intersection, the road continues through northern Maypearl, passing several rows of houses and small businesses.

The highway spends a very short period of time traveling west, before turning northeast again, and becoming Main Street.

After a few miles of passing several streets, FM 157 splits off of Business US 287 heading due north.

After interchanging with I-20, The highway slants toward the northeast for about 2.5 miles before reaching Pioneer Parkway (Spur 303).

Seven days later, on June 11, 1945, the highway was extended from US 287 through Venus and southward to the southern border of Ellis County.

[2] The route was extended on October 25, 1955, to a junction with FM 66 in Maypearl, adding approximately 8.8 miles (14.2 km) to the overall length.

[2] On June 27, 1995, the stretch of the highway traveling from SH 121 south to US 287 was redesignated as UR 157, approximately 17.3 miles (27.8 km).