It is a farm to market road existing entirely within Galveston County that connects Santa Fe to Texas City via a short stretch of freeway known as the Emmett F. Lowry Expressway.

[3] From there, the route heads north slightly and then east, through farmland approximately 5.5 miles (8.9 km) towards junctions with FM 2004 and Interstate 45 (I-45) near Texas City.

The freeway section, complete with frontage roads, is known as the Emmett F. Lowry Expressway and runs approximately five miles (8.0 km) between I-45 and SH 146 in Texas City.

[4] The expressway is named after Emmett F. Lowry, who served as mayor of Texas City from 1964 until his death in 1989 and was instrumental in the construction of the thoroughfare.

The eastern end of FM 1764 is at the intersection of 9th Avenue North and 14th Street, adjacent to Texas City High School.