Fazio Giovanni Santori was born in Viterbo in 1447.
[1] He was the pedagogus of Giuliano della Rovere, the future cardinal and future Pope Julius II; when della Rovere became a cardinal, he took Santori into his household.
[1] Pope Julius II made him a cardinal priest in the consistory of 1 December 1505.
[1] He received the red hat and the titular church of Santa Sabina on 17 December 1505.
[1] He was initially buried in San Lorenzo in Lucina; his remains were later transferred to St. Peter's Basilica.