Federico Guillermo Lussenhoff (born 14 January 1974) is an Argentine former professional footballer who played as a central defender.

Born in Venado Tuerto, Santa Fe Province, Lussenhoff began his career at Rosario Central, and also had spells at San Lorenzo de Almagro, Mexican clubs Toros Neza and Cruz Azul and CD Tenerife and RCD Mallorca in Spain.

[2][3] In the latter nation, to where he arrived in January 1999, he was relegated from La Liga in his first season, then became an undisputed starter as the Canary Islands side returned to the top flight in 2001, under Rafael Benítez.

[5] In 2005, after 192 competitive matches in five and a half seasons in Spanish football, Lussenhoff returned to his country and signed with Club Atlético River Plate.

[6] Lussenhoff returned to Spain on 20 January 2010, as he joined his compatriot Nestor Gorosito – coach – at Xerez CD as director of football.