As in Feeding Frenzy, players have to control several fast-growing marine predators who are out to uncover a mystery lurking in the ocean.

The game aims to avoid predators and obstacles while eating other smaller fish and creatures, eventually reaching the top of the food chain.

Feeding Frenzy 2 includes 60 new levels which feature scenery such as new underwater worlds, coral reefs, deep sea caves, and sunken ships, including above-water challenges.

The story mode has the player control a small butterflyfish named Boris.

Along the way, the player encounters new prey and predators, both friendly and unfriendly, and must stop an alien fish named "The Intruder" from destroying the ocean.