Since 2006, Jones has appeared in the films Northanger Abbey (2007), Brideshead Revisited (2008), Chéri (2009), The Tempest (2010), The Amazing Spider-Man 2 (2014), and True Story (2015).

[1] She has since portrayed Ruth Bader Ginsburg in the biopic On the Basis of Sex (2018), and has starred in the streaming films The Aeronauts (2019), The Midnight Sky (2020) and The Last Letter from Your Lover (2021), as well as the period drama The Brutalist (2024), which earned her a nomination for the Academy Award for Best Supporting Actress.

[12] She took the leading role in the 2007 ITV adaptation of Jane Austen's Northanger Abbey, and starred in Polly Stenham's That Face at the Royal Court Theatre in April 2007.

In 2008, Jones appeared in the films Brideshead Revisited and Flashbacks of a Fool,[13] the Doctor Who episode "The Unicorn and the Wasp" and a revival of Enid Bagnold's The Chalk Garden at the Donmar Warehouse theatre in London.

On 29 January 2011, Jones won a Special Jury Prize (Dramatic) at the Sundance Film Festival for her performance as Anna in Drake Doremus's Like Crazy.

[4] Jones performed in Luise Miller, a new translation of Schiller's Kabale und Liebe by Mike Poulton at the Donmar Warehouse theatre in London, in June and July 2011.

Jones, previously unfamiliar with Ternan, learned about her life through research,[21] and reflected that she knew she was "in for a challenge" when choosing to work on the film, citing the experience of director Ralph Fiennes and how "methodically done" his performance was.

[32] In February 2015, she was cast as Jyn Erso in the Star Wars stand-alone film Rogue One, with Gareth Edwards directing.

[33] Jones's agent recommended the role to her,[34] and she enjoyed the character's search for an identity, drawing inspiration in her movements from Ronda Rousey.

[38] In late 2018, Jones starred in On the Basis of Sex, a biography of United States Supreme Court Justice Ruth Bader Ginsburg, directed by Mimi Leder and co-starring Armie Hammer and Justin Theroux.

[39] She then reunited on-screen with Redmayne in the biographical adventure The Aeronauts (2019), joined George Clooney in Netflix's science fiction film The Midnight Sky (2020), and starred in the romantic drama The Last Letter from Your Lover (2021), an adaptation of Jojo Moyes' 2011 novel of the same name.

Jones starred in the thriller Dead Shot,[40] alongside Aml Ameen, Mark Strong and Sophia Brown, in 2023.

[43] Jones appeared in the 2024 film The Brutalist, portraying the Holocaust-survivor wife of the central character, for which she received a nomination for the Academy Award for Best Supporting Actress.