In 1990, the murder of his nephew Roy Jou Vargas at six years of age in a conflict occasioned by a non-indigenous landowner, propelled him into public activism.
[2] During Vargas' term as leader, the TIPNIS indigenous community was engaged in an extended campaign against the building of the Villa Tunari–San Ignacio de Moxos Highway through the territory, a project championed by President Evo Morales.
Vargas was one of the leaders of 2011 and 2012 marches by the Confederation of Indigenous Peoples of Bolivia (CIDOB) against the project.
However, in 2012 the Bolivian government carried out a disputed consultation process, and concluded that intangibility should be lifted and the roadway proceed.
[4] With 24,685 out of 27,403 polling stations having reported in the Green Party had gained 126,958 votes in the presidential elections, a total of 2.79%.