Fifth Third Center is a skyscraper located in downtown Cleveland, Ohio along Superior Avenue.

The building has 27 stories and rises to a height of 446 ft (136 m), encompassing 515,000 square feet (47,800 m2).

Designed by RTKL Associates, the building was originally constructed as Bank One Center in 1991.

In 1989, developer John Galbreath, who had a hand in the Erieview and One Cleveland Center project, worked with Nissi Iwho Realty Trust in Tokyo to build a new tower.

In 2002, Bank One was acquired in a massive merger with JP Morgan Chase.