After being blamed for a party which he didn't throw or have any knowledge of, that resulted in many damages, young Darren (Lou Taylor Pucci) loses his scholarship.

His roommate, Coleman (John Hensley), who actually threw the party, sympathizes with Darren and gives him a stash of fifty ecstasy pills.

Darren sells to many weirdos, including a dominatrix who wants the pills so her "pets" can be numb when she has sex with them.

The brother of this roommate, a seemingly mentally-challenged and over-zealous white-collar employee named Ralphie (Eddie Kaye Thomas), is obsessed with Diff'rent Strokes.

The next day, Darren feels defeated, but discovers that Coleman paid his tuition in full and is leaving the college.