[2] She studied literature and philosophy at the Università Cattolica del Sacro Cuore in Milan, and then worked as a teacher.

Having become a member of the youth movement of Azione Cattolica, she served as its president while studying for a master's degree, also joining the Italian Catholic Federation of University Students in 1940.

[2] After joining the Christian Democracy party, Delli Castelli became provincial secretary of its women's section.

[2] Although she lost her seat in parliament the June 1953 elections, she returned to the Chamber of Deputies in December 1953 when she replaced Giuseppe Castelli Avolio [it], who had resigned after being appointed to the judiciary.

Delli Castelli subsequently worked for RAI until 1975, focussing on children's television, after which she moved to Pescara.