The medical center had 9,678 admissions, 3,162 inpatient procedures, 7,704 outpatient surgeries, and its emergency department had 47,208 visits.

[2] Firelands Regional Medical Center is the only hospital in Erie County serving more than 10,000 inpatients and over 45,000 ER patients annually and is the largest year-round employer.

In 1923, the Diocesan boundaries were redrawn and the Sisters of St. Francis of Sylvania, Ohio assumed sponsorship.

The Firelands Regional Medical Center School of Nursing is fully accredited and located on hospital property.

In 2009, Firelands Regional Medical Center was listed as one of the 100 Best Places to Work in Healthcare.