[1][13][14][15][16] In 1833, the Constitution of Massachusetts was amended, and it effectively cut all ties between the church and the local government, which included funding.

[8][17] This led to the founding of the First Parish in Brookline as opposed to the Church of Christ, as it had previously been known.

[1] The third meeting house was constructed and dedicated in 1848 by Edward C. Cabot near the end of John Pierce's ministry, who is the longest serving minister in the history of the church.

[18] However, it was ultimately decided that the church was Unitarian, though no official change was initially made.

The construction of the fourth meeting house was completed in 1893, and the dedication happened on April 19 of the same year.

[20][21][22] The church's interior contains 21 individual stained glass windows, designed mainly by Louis C. Tiffany, Sarah Whitman, and Charles Connick.