Fissurina karnatakensis is a species of corticolous (bark-dwelling) script lichen in the family Graphidaceae.

It grows on tree trunks in exposed conditions along roadsides within moist forests, particularly in Karnataka, a state known for its many endemic lichen species.

[2] The thallus of Fissurina karnatakensis is brown and slightly glossy, with a smooth to uneven texture with cracks.

The ascomata, or fruiting bodies, are lirelline in form and immersed, matching the colour of the thallus.

[2] Chemical spot tests reveal that Fissurina karnatakensis has K+ (yellow), C−, KC−, P+ (rust-red), and UV− reactions.