Cells are described as straight or slightly curved rods, 2-10 microns long, and occur singly or in pairs.

[8] Flavonifractor plautii has a genome consisting of a single circular chromosome with 3,985,392 base pairs, with a G+C content of 60.9%.

Flavonifractor plautii is highly prevalent in the human gastrointestinal tract, and is known to be a proficient producer of butyrate.

Armstrong et al. found preferential binding of IgG from Crohn’s disease patients to F. plautii as compared to non-IBD and ulcerative colitis derived microbes.

They also demonstrated that F. plautii had invasive potential in vitro using a fluorescence microscopy based assay using intestinal epithelial cells in culture.