She is best known for writing and directing The Runaways, for directing music videos for performers including Dua Lipa, Sam Smith, Jimmy Page and Robert Plant (of Led Zeppelin fame), Marilyn Manson, Christina Aguilera, Justin Timberlake, Rihanna, Leonard Cohen, Katy Perry, Björk, The White Stripes, and David Bowie, and commercials for brands such as Gucci, MAC, Target, and Nike.
Her very innovative, but also very disturbing video works, located in sceneries she once described as "entropic underworlds inhabited by tortured souls and omnipotent beings," attracted a number of very prominent musicians.
With her photography and sculpture installations she had solo exhibitions in Hamilton and Toronto, New York City, Brescia (Italy), Gothenburg (Sweden), and London.
Her photographs also were included in numerous group exhibitions, together with artists such as Cindy Sherman, Joel-Peter Witkin, and Francesco Clemente.
"[2] She has an affinity for strange yet alluring things and created a flesh-esque chair to appeal to the sexual tension and desire to the spectator.