In the 2020 redistricting cycle, the district was moved out of its coastal counties and into Orlando's western suburbs.

From 1993 to 2013, the former 11th district had encompassed most of the city of Tampa and its suburbs and the shoreline of southeastern Hillsborough County.

[6] Since the redistricting for the 2022 elections, the district includes Bay Lake, home to all four theme parks of Walt Disney World.

In 1986, weeks before the Challenger disaster, the district's then-congressman, Bill Nelson, (who later served as U.S.

Senator from Florida from 2001 to 2019, and has been NASA Administrator since 2021) flew on board the Space Shuttle Columbia as part of mission STS-61-C. From 1993 to 2013 the district was based in Tampa plus the shoreline of Tampa Bay; the city's long-serving congressman Sam Gibbons retired in 1997 after nearly 35 years in the House.