State Road 33 begins in Lakeland off U.S. Route 92 (US 92) east of the intersection with US 98 and heads north along the vicinity of the west bank of Lake Parker.

The route turns more to the east away from I-4, until it curves north at the northern terminus of Florida State Road 659.

Some Google Street View images still mistakenly show Iowa Avenue as being part of SR 33.

It began at US 98 in Eaton Park, ran north through Crystal Lake and Combee Settlement at US 92, and finally terminated at SR 33 south of Interstate 4.

Today it is designated as Florida State Road 659, though the old route number still shows up in many street name signs and on Google maps.