The road operated as the southern terminus of the expressway in the early 1980s before Interstate 75 extended south to Naples.

The freeway heads northeast coming to an at-grade signalized intersection with Honore Avenue.

[2][3] State Road 681 opened to traffic in 1980 when segments of Interstate 75 between Tampa and Naples were still under construction.

[4] In April 2016, the final phase of Sarasota County's Honore Avenue extension was completed.

The project extended Honore Avenue from SR 681 to Laurel Road, providing signalized intersections at both limits.