The entire roadway, stretching from Indiantown at its western terminus in Martin County to its terminus 2 miles east of its intersection with US 1 in Port St. Lucie in St. Lucie County, currently carries three different designations - SR 716, CR 76A, and CR 726.

33 miles from the extreme southern beginning of the roadway in Indiantown, the State Road 716 designation begins as a 6-lane roadway at the west end of the overpass carrying the road over Florida's Turnpike and its corresponding exit/entrance ramps with Port St. Lucie Blvd (Exit 142) in Port St. Lucie But it roadway goes west to palm city at Martin Highway/ SR714 a state road the ends west by the Okeechobee County.

At the middle, SR 716 crosses over a pair of bridges over Long Creek and the North Fork of the St. Lucie River (both waterways part of the North Fork St. Lucie River Aquatic Preserve), the only undeveloped section of the road and St.Lucie river goes through to Indiantown and ends on Lake Okeechobee.From here, Port St. Lucie Boulevard continues east through more residential/commercial development, where the SR 716 designation terminates at US 1.

Currently, that section is marked "active off the SHS" on the FDOT Straight Line Diagram for SR 716.

In the early 2000s, an extension connecting the southern end of Port St. Lucie Boulevard at the Martin/St.