The snails feed on microbial organisms and detritus attached to surfaces.

Floridobia species tolerate low dissolved oxygen levels found near spring vents, which helps protect then from most fish predators.

[3] A study of F. floridana reported that the increased presence of cyanobacteria in its diet slowed its growth.

[4] Species of Floridobia were classified in the genus Cincinnatia prior to 2002, based on the structure of the penis.

Thompson and Hershler erected the new genus of Floridobia in 2002, moving 15 species from Cincinnatia, based on the structure of the penis and the female genitalia.