This nanometric features enables the handling of liquid volumes at the femtoliter (fL) scale as well as force controlled manipulations of sub-micron objects.
Compared to the traditional glass micropipettes FluidFM probes are much more gentle to soft samples such as cells.
In addition to standard AFM experiments, FluidFM provides the possibility to perform countless other applications, such as single cell injection and adhesion as well as nanolithography and spotting.
Single cell injection is an important tool for life sciences, biology and medicine.
With FluidFM the success rate is almost 100%, in contrast to other methods, because the probes are small, sharp and force sensitive.
[3][4][5] By measuring the adhesion of single cells, important information for different topics in biology and materialscience can be obtained.
With FluidFM it is possible to increase the rate in which these experiments can be performed, and even to assess the adhesion of spread cells.
The spots are created when the nanopipette makes contact with the surface and the substance is released of the probe with a short pressure pulse.