Fly spray contains chemicals (including many organophosphate compounds) that bind to and permanently block the action of an enzyme called acetylcholinesterase.
[1] Acetyl choline (ACh) is the nerve transmitter substance released by motor neurones (at a site called the neuromuscular junction) to stimulate muscle contraction.
Like many insecticides, fly spray can be toxic to a host of other organisms including birds, fish, beneficial insects, and non-target plants.
[3] In the United States, fly sprays often contain the powerful insect toxin dichlorvos which is often targeted by environmental groups as a carcinogenic compound.
[4][failed verification] While the small quantities found in fly spray may be negligible, the insect toxin can contaminate soil, water, turf, and other vegetation if disposed improperly.