Folate receptors bind folate and reduced folic acid derivatives and mediates delivery of tetrahydrofolate to the interior of cells.
Polyglutamate forms are biologically active enzymatic cofactors required for many folate-dependent processes such as folate-dependent one-carbon metabolism.
These proteins are attached to the membrane by a GPI anchor.
[2] A riboflavin-binding protein required for the transport of riboflavin to the developing oocyte in chicken also belong to this family.
Human proteins from this family include: