It stars Wayne Lai, Maggie Cheung, Kate Tsui, Ron Ng, Aimee Chan, Edwin Siu, Nancy Wu & Ruco Chan in the reboot of the Forensic Heroes series, featuring new stories and characters.

DCS Senior Inspector Ada Ling (Kate Tsui) and Sergeant Lee Chin-fung (Ron Ng), better known as Wind, work together and crack many murder cases.

[3] Charmaine Sheh was originally set to be the lead actress, however after suffering injuries slipping on a patch of ice in Shanghai, she was forced to withdraw from the series.

Hui and Professor T. Wing Lo of the City University of Hong Kong conducted a study to determine if the "CSI Effect" was taking place in Hong Kong due to the popularity of Forensic Heroes III.

Despite the effects of the media on participants' perception of legal evidence, it did not affect their overall legal-decision making.