Fort Hoskins was garrisoned by a number of companies of soldiers throughout its short existence, and future Union Civil War generals Christopher Columbus Augur and Phil Sheridan were stationed there.

Two soldiers who were stationed at the fort during the American Civil War kept journals of their experiences: Royal A. Bensell and William M. Hilleary.

Fort Hoskins played an indirectly important role in local and state history because of the leadership of several out-of-state soldiers who decided to stay in the area after they were mustered out of the army.

The fort never saw any action, though a bloodless insurrection by Native Americans at Yaquina Bay was put down by the soldiers.

[10] According to author Ralph Friedman the yards, roundhouse, and covered bridge were all gone by 1990, and the only business remaining by 1972 was the tavern.

[8][9] The Samuel Frantz (Dunn-Frantz) House was converted to a residence after serving as the Fort's infirmary; it is now part of the county park.