Under the terms of the Treaty of Paris (1783) that ended the American Revolutionary War the region south of the Great Lakes and between the Ohio and Mississippi Rivers was assigned to the United States.

In the early 1790s, the Lieutenant Governor of Upper Canada, John Graves Simcoe, made an aggressive effort to aid the "Western Confederacy" of Native American tribes (the Shawnee, Miami, Wyandot, and others) in the Maumee and Wabash River watersheds in their ongoing war with American settlers.

The fort was a log stockade, which had four bastions, each capable of mounting four cannon, a river battery, barracks, officers' quarters, supply buildings, and various shops.

Just south of Fort Miami, encountering a barricade erected by the Native Americans and a small party of Canadian militia, he ordered a charge and dispersed his adversaries in the Battle of Fallen Timbers.

Beaten and disillusioned, the Native Americans dispersed and one year later their tribal elders gathered at Fort Greenville to negotiate with Wayne.

Today, the site of Fort Miami sits as a small enclave within a residential development.