The assumed course of study follows the Smart Core curriculum developed by the Arkansas Department of Education (ADE), which requires students to complete at least 22 units to graduate.

Students complete regular courses and exams and may self-select Advanced Placement (AP) coursework and exams with the opportunity for college credit.

For 2012–14, the Fouke Panthers compete in the 3A Classification in the 3A Region 6 (football) and 3A Region 7 (basketball) conferences as administered by the Arkansas Activities Association (AAA).

The Panthers participate in football, baseball, softball, and track (boys/girls).

[3] A trap shooting team competes as a member of the Arkansas Youth Sports Program (AYSSP) South Region administered by the Arkansas Game and Fish Commission.