The museum is located on a site formerly used for wagon and automobile body construction.

[1][5][6] Its collections span 100 years of automotive history and include over 20 automobiles that are displayed on a rotating basis, generally for periods of three to six months.

[2][6][7][8] At any one time, the museum has approximately 15 cars on display, as well as a few motorcycles and a variety of automobilia.

[2][7] The Four States Auto Museum hosts an annual car show in conjunction with Texarkana's RailFest,[9][10] as well as the annual Fall Fun Car Show & Swap Meet, both of which serve as fundraisers for it.

[8] The museum also hosts various educational events, parties, school tours, and weddings.