[2] San Antonio High School was established in 1882.

In 1917, it was rebuilt and renamed Main Avenue High School.

Students from the old Main Avenue High School who intended to continue pursuing academic studies were sent to the newly built Thomas Jefferson High School.

[3] In 2017, The Centers for Applied Science and Technology (CAST) opened a charter school in Fox Tech's two freshly-renovated buildings, which were the Freshman buildings.

This CAST school was named CAST Tech which uses computer-based learning to allow students to progress more quickly in areas where they have mastered concepts, allowing them to dive more deeply into projects and areas of great interest.