The Françoise river is a tributary of the rivière aux Anglais flowing in the unorganized territory Rivière-aux-Outardes, in the Manicouagan Regional County Municipality, in the administrative region of Côte-Nord, in the province of Quebec, in Canada.

The Françoise river has its source on the Canadian Shield, at a small unidentified lake (length: 0.24 km (0.15 mi); altitude: 441 m (1,447 ft)).

The mouth (south side) of this small forest lake is located 9.0 km (5.6 mi) northeast of the confluence of the Françoise river and the rivière aux Anglais, at 0.8 km (0.50 mi) south-west of a bay in lake Franquelin and 35.2 km (21.9 mi) north-west of the confluence of the rivière aux Anglais and Baie des Anglais on the north shore of the Gulf of St. Lawrence.

From the head lake, the course of the Françoise river descends on 11.1 km (6.9 mi) entirely in the forest zone, with a drop of 182 m (597 ft), according to the following segments: The Françoise river flows on the northeast bank of the upper course of the rivière aux Anglais, in the unorganized territory of Rivière-aux-Outardes.

The toponym "Françoise River" was formalized on August 2, 1974, at the Place Names Bank of the Commission de toponymie du Québec.