She was born in November 1592 with the exact date unknown; her only sibling, Philippe Louis, died in 1590 aged one making her the heiress to a large private fortune.

As part of their peace they drew up a marriage contract in 1596 whereby his daughter, would marry Henry's legitimised son.

[1] The French and Spanish then signed the Peace of Vervins on 2 May 1598 when Françoise was 6; part of the treaty again stipulated that the young Françoise would be engaged to the illegitimate child of Henry IV, César de Bourbon, Duke of Vendôme.

Her husband died disgraced in 1665, having been involved in the Fronde and having been accused of trying to poison Cardinal Richelieu.

Other fiefs that Françoise owned were the princedom of Martigues, the duchy of Étampes and the seigneurie of Ancenis.